Curcumin Plus Vitamin D May Help Prevent Alzheimer's
Monday, October 26, 2009 at 3:00PMIn other Alzheimer's news, curcumin, a component of the spice turmeric, may be the reason why elderly villagers in India who consume lots of curry have one of the world's lowest rates of Alzheimer's disease. Now, a team of researchers in California has discovered that combining curcumin with vitamin D3 may prompt the immune system to mobilize against amyloid beta, the substance that forms the plaques in the brain characteristic of Alzheimer's. So far, the investigators found evidence of this effect in tests with blood 
samples from nine Alzheimer's patients, a patient with cognitive impairment and three healthy controls. They incubated immune system cells called macrophages which clean up waste products - including amyloid beta - with vitamin D and curcumin. The study showed that curcumin boosted the binding of amyloid beta to the macrophages and that vitamin D strongly stimulated the uptake and absorption of amyloid beta in macrophages. At this point, the researchers aren't recommending any doses of either curcumin or vitamin D for Alzheimer's prevention or treatment, but they are planning bigger studies with more patients. The findings were published in the July 2009 issue of the Journal of Alzheimer's Disease.
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